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Hai Fu Dao ®UsgHIFUa」 Also known as "Focused Ultrasound Knife", it is the abbreviation for "Ultrasound guided High Intensity Focused Ultrasound Ablation". This is a new technology that can kill tumors in the body without the need for skin incision, puncture, or bleeding. It is also known as "non-invasive surgery".
Hai Fu Dao ®UsgHIFUa」 As a non-invasive treatment, the principle is similar to that of sunlight that can be focused through a magnifying glass. It emits dispersed ultrasound energy from outside the body, safely penetrates normal tissues, and accurately focuses on the target area inside the body. Using the inherent characteristics of ultrasound - thermal effect, cavitation effect, etc. - the lesion tissue in the target area instantly reaches a high temperature of over 60 ° C, causing irreversible coagulation necrosis, and causing almost no damage to the sound channel and tissues outside the target area.
hifu ®UsgHIFUa It is a technique that can focus low-energy ultrasound waves from outside the body into a highly concentrated area of energy inside the body, and through thermal and cavitation effects, irreversible coagulative necrosis is formed in the tissue of this energy concentrated area. It is widely used in tumor treatment.
For HIFU therapy, ablation can be achieved when the temperature is maintained at 60 ° C for more than 1 second or at an equivalent heat dose, resulting in protein denaturation and irreversible coagulation necrosis of the target tissue. Due to its high focus, HIFU therapy has the characteristic of only ablating the target tissue without damaging the surrounding normal tissue. Histopathology revealed a clear boundary of less than 50 µ m between the coagulative necrosis zone and the surrounding area, containing only 5-7 layers of cells. HIFU has high precision and controllability in causing tissue damage.
Cavitation effect is another critical mechanical effect in addition to thermal effect during HIFU thermal ablation process. When ultrasound is applied to a liquid medium, tiny bubble nuclei in the liquid are activated under the action of ultrasound, exhibiting a series of processes such as oscillation, growth, compression, and collapse, known as acoustic cavitation, abbreviated as cavitation. The existence of cavitation effect will cause high-intensity ultrasound to form bubbles at the target site. The rupture of bubbles can generate high-pressure shock waves (20-30000 bars) and high temperatures (2000-5000K) in nearby small areas, damaging the surrounding tissues in a small range and further enhancing the ablation effect of HIFU on tissues.
hifu ®Usg-HIFUa This medical procedure has been used for clinical treatment for over 20 years, with over 500 international intellectual property rights obtained. It has entered 30 countries or regions including China, the United Kingdom, Germany, Italy, Hong Kong, Singapore, and South Korea, and has accumulated over 240000 treatment cases worldwide. It has been included in medical treatment guidelines such as The National Institute for Health and Care Excellence (NICE) Guidelines in the United Kingdom, OG Guidelines of the Hong Kong College of Obstetrics and Gynecology, Chinese Expert Consensus on the Diagnosis and Treatment of Uterine Fibroids and Chinese Expert Consensus on the Diagnosis and Treatment of Uterine Adenomyosis by the Chinese Society of Obstetrics and Gynecology.
